The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.m

Vascultis (pulmonary, extrathoracic or systemic)-ANCA status unknown or negative)

Publications

Dias OM, Nascimento ECTD, Chate RC, Kairalla RA, Baldi BG

Eosinophilic pneumonia: remember topical drugs as a potential etiology.

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. 2018;44(6):522-524

Starr MR, Tillema JM, Ytterberg SR, Bhatti MT, Chen JJ

Minocycline-Induced Vasculitis Presenting as a Third Nerve Palsy.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 2019;39(2):240-241

Baratta JM, Dyck PJ, Brand P, Thaisetthawatkul P, Dyck PJ, Engelstad JK, Goodman B, Karam C

Vasculitic neuropathy following exposure to minocycline.

Neurology(R) neuroimmunology & neuroinflammation. 2016;3(1):e180

Garg N, Altowaijri GH, Nesbit GM, Gultekin SH, Bourdette DN

Minocycline-associated vasculitis of extracranial branches of vertebral arteries presenting as myelopathy.

Neurology(R) neuroimmunology & neuroinflammation. 2014;1(1):e7