The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.a

Pulmonary edema, noncardiogenic (NCPE)

Publications

Buie SE, Pratt DS, May JJ

Diffuse pulmonary injury following paint remover exposure.

The American journal of medicine 1986 Oct;81;702-4 — 1986 Oct — 702-4

Snyder RW, Mishel HS, Christensen GC

Pulmonary toxicity following exposure to methylene chloride and its combustion product, phosgene.

Chest 1992 Mar;101;860-1 — 1992 Mar — 860-1