The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Carboxyhemoglobinemia
Publications
Carbon monoxide poisoning secondary to inhaling methylene chloride.
British medical journal 1980 Nov 29;281;1461 — 1980 Nov 29 — 1461
Diffuse pulmonary injury following paint remover exposure.
The American journal of medicine 1986 Oct;81;702-4 — 1986 Oct — 702-4
Hyperbaric oxygen for methylene chloride poisoning: report on two cases.
Annals of emergency medicine 1989 Jun;18;691-5 — 1989 Jun — 691-5
Treatment of methylene chloride induced carbon monoxide poisoning with hyperbaric oxygenation.
Military medicine 1990 Nov;155;570-2 — 1990 Nov — 570-2
Pulmonary toxicity following exposure to methylene chloride and its combustion product, phosgene.
Chest 1992 Mar;101;860-1 — 1992 Mar — 860-1
Chronic carbon monoxide poisoning caused by methylene chloride paintstripper.
Medicine, science, and the law 1978 Oct;18;238 — 1978 Oct — 238
Elevated carbon monoxide levels from exposure to methylene chloride.
JAMA 1978 Jun 02;239;2341 — 1978 Jun 02 — 2341