The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XI.r

Death following exposure or poisoning

Typically from catastrophic bronchospasm and the locked lung

Publications

Spitz DJ

An unusual death in an asthmatic patient.

The American journal of forensic medicine and pathology 2003 Sep;24;271-2 — 2003 Sep — 271-2

Fallowfield JM, Marlow HF

Propranolol is contraindicated in asthma.

BMJ (Clinical research ed.) 1996 Dec 07;313;1486 — 1996 Dec 07 — 1486