The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.ae

Radiation recall pneumonitis

Publications

Merten R, Hecht M, Haderlein M, Distel L, Fietkau R, Heinzerling L, Semrau S

Increased skin and mucosal toxicity in the combination of vemurafenib with radiation therapy.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 2014 Nov;190;1169-72 — 2014 Nov — 1169-72

Forschner A, Zips D, Schraml C, Röcken M, Iordanou E, Leiter U, Weide B, Garbe C, Meier F

Radiation recall dermatitis and radiation pneumonitis during treatment with vemurafenib.

Melanoma research 2014 Oct;24;512-6 — 2014 Oct — 512-6