The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Takahashi K, Tanaka S, Watanabe M, Yamakage M

Rocuronium-induced anaphylaxis: a case report.

JA clinical reports. 2019;5(1):81

Sakamoto S, Horiuchi T, Takazawa T, Hoshino Y, Takahashi K, Saito S

[A Case of Rocuronium-induced Anaphylaxis in a Man with Kounis Syndrome in which Basophil Activation Test was Valuable in Determining the Causative Agent].

Masui. The Japanese journal of anesthesiology. 2017;66(4):424-430

Tanoue R, Takei Y, Hayashida Y, Harada H

A Case of Rocuronium-Induced Anaphylactic Shock in an Asthmatic Child.

Anesthesia progress. 2018;65(1):58-59

Esteves LO

Case of anaphylaxis induced by rocuronium treated with sugammadex.

Brazilian journal of anesthesiology (Elsevier). 2013;63(6):511

Oh YJ, Lee HJ

Multiple cross-reactivity to several types of neuromuscular blocking agents in a patient with rocuronium anaphylaxis.

Korean journal of anesthesiology. 2013;65(5):473-4

Neal SM, Manthri PR, Gadiyar V, Wildsmith JA

Histaminoid reactions associated with rocuronium.

British journal of anaesthesia. 2000;84(1):108-11

Yee R, Fernandez JA

Anaphylactic reaction to rocuronium bromide.

Anaesthesia and intensive care. 1996;24(5):601-4