The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Negative pressure pulmonary hemorrhage (NPPH)
Publications
Diffuse Alveolar Hemorrhage After Orotracheal Extubation Probably Induced by Sevoflurane Inhalation.
Archivos de bronconeumologia 2021 Jan 28;; — 2021 Jan 28
Delayed presentation: negative pressure pulmonary hemorrhage.
Journal of clinical anesthesia 2012 Sep;24;490-3 — 2012 Sep — 490-3
Negative pressure post-tracheal extubation alveolar hemorrhage.
Anesthesia and analgesia 2001 Jan;92;273-5 — 2001 Jan — 273-5