The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.a

Pulmonary edema, noncardiogenic (NCPE)

Publications

Shustack A, Noseworthy TW, Johnston RG, Anderson BJ, Johnston D, Bailey RJ

Noncardiogenic pulmonary edema during intrabiliary infusion of mono-octanoin.

Critical care medicine 1986 Jul;14;659-60 — 1986 Jul — 659-60

Hine LK, Arrowsmith JB, Gallo-Torres HE

Monooctanoin-associated pulmonary edema.

The American journal of gastroenterology 1988 Oct;83;1128-31 — 1988 Oct — 1128-31