The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XIV.a

Methemoglobinemia

Publications

Zhao L, Jian T, Shi L, Li Y, Wen Z, Guo L, Li Q, Jian X

Case report: Methemoglobinemia caused by nitrobenzene poisoning.

Frontiers in medicine. 2023;10:1096644

Agrawal A, Gutch M, Arora R, Jain N

Acute cardiogenic pulmonary oedema with multiorgan dysfunction--still to learn more about nitrobenzene poisoning.

BMJ case reports. 2011;2011

Gupta A, Jain N, Agrawal A, Khanna A, Gutch M

A fatal case of severe methaemoglobinemia due to nitrobenzene poisoning.

Emergency medicine journal : EMJ. 2012;29(1):70-1

Perera M, Shihana F, Kularathne K, Dissanayake D, Dawson A

Acute methaemoglobinaemia after massive nitrobenzene ingestion.

BMJ case reports. 2009;2009