The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

IV.d

Cough (lone)

Publications

Milazzo L, Cattaneo D, Cheli S, Ferraris L, Colella E, Clementi E, Gervasoni C

ACE inhibitors and ribavirin-associated cough: a common undefined predisposing factor?

European journal of clinical pharmacology 2013 Mar;69;743-5 — 2013 Mar — 743-5

Dicpinigaitis PV, Weiner FR

Chronic cough associated with interferon/ribavirin therapy for hepatitis C.

Journal of clinical pharmacy and therapeutics 2011 Jun;36;416-8 — 2011 Jun — 416-8