The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Lupus - Lupus syndrome (see also Vd)
Publications
Do selected drugs increase the risk of lupus? A matched case-control study.
British journal of clinical pharmacology. 2010;70(4):588-96
Why minocycline can cause systemic lupus - a hypothesis and suggestions for therapeutic interventions based on it.
Medical hypotheses. 2004;63(1):31-4
Minocycline induced lupus: case series in the West of Scotland.
The Journal of rheumatology. 2001;28(5):1004-6
Minocycline-induced lupus: clinical features and response to rechallenge.
Rheumatology (Oxford, England). 2001;40(3):329-35
Coexistent minocycline-induced systemic lupus erythematosus and autoimmune hepatitis.
Seminars in arthritis and rheumatism. 1998;28(3):187-92
Comparative safety of tetracycline, minocycline, and doxycycline.
Archives of dermatology. 1997;133(10):1224-30