The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Anaphylaxis-Anaphylactoid reaction (can be fatal)
Publications
Anaphylaxis mortality in the perioperative setting: Epidemiology, elicitors, risk factors and knowledge gaps.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2024;54(1):11-20
A case report: anaphylaxis to cefazolin during renal transplant surgery.
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology. 2021;17(1):54
Perioperative anaphylaxis to cefazolin.
Allergy and asthma proceedings. 2004;25(1):23-6
Complete recovery from prolonged cardio-pulmonary resuscitation following anaphylactic reaction to readministered intravenous cefazolin.
Acta anaesthesiologica Scandinavica. 2003;47(2):230-2
Anaphylactic reaction to intravenous cefazolin.
Nurse anesthesia. 1993;4(4):188-92
Anaphylactic reaction to intravitreal cefazolin.
Retina (Philadelphia, Pa.). 1994;14(2):187-8