The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)
Publications
Refractory hypoxemia due to sodium polystyrene sulfonate (kayexalate) aspiration.
Annals of the American Thoracic Society 2014 Jul;11;993-5 — 2014 Jul — 993-5
Pulmonary disease due to aspiration of food and other particulate matter: a clinicopathologic study of 59 cases diagnosed on biopsy or resection specimens.
The American journal of surgical pathology 2007 May;31;752-9 — 2007 May — 752-9
Kayexalate (sodium polystyrene sulfonate) aspiration.
Archives of pathology & laboratory medicine 2005 Jan;129;125 — 2005 Jan — 125