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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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XI.bj

Hemolytic anemia

See also under 'Methemoglobinemia' in section XIV

Last update : 01/01/1970
 

Causative drugs

1

Amyl-nitrite, butyl-nitrite, isobutyl-nitrite ('Poppers')

VIII.d VIII - Central-large-upper airway (incl. pharyngeal-nasal) involvement
VIII.d - Thermal (burns, frostbite), chemical or caustic injury on the face, mouth, tongue, pharynx or upper airway
XI.a XI - Miscellaneous
XI.a - Cyanosis, a low SpO2 and normal measured PaO2
XI.bj XI - Miscellaneous
XI.bj - Hemolytic anemia
XIV.a XIV - Hemoglobinopathies - Abnormal hemoglobin states (acquired)
XIV.a - Methemoglobinemia
2
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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