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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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XXIV.k

Veterinary: Granulomatous interstitial pneumonia

Last update : 01/01/1970
 

Causative drugs

1

Charcoal, activated (aspirated)

I.s I - Interstitial/parenchymal lung disease
I.s - A mass or masses
II.b II - Pulmonary edema - Acute lung injury - ARDS
II.b - ARDS - Acute lung injury
IV.c IV - Airway involvement
IV.c - Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)
IV.r IV - Airway involvement
IV.r - Airway pigmentation (black, bluish, petechial)
V.x V - Pleural and/or pericardial involvement
V.x - Black pleural effusion
XV.q XV - Pathology
XV.q - Path: Foreign body deposits/granulomatous reaction
XV.aa XV - Pathology
XV.aa - Path: Foreign body bronchiolitis (see also IVi)
XXIV.k XXIV - Veterinary medicine
XXIV.k - Veterinary: Granulomatous interstitial pneumonia
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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