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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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XVIII.d

Eye catcher: Mercury embolism (in lung and/or in other tissues)

In the form of multiple branched intravascular densities. See also under XVIIIL (acrylate embolism, to which the condition may resemble). Densities and mercury droplets on Imaging at injection site (e.g. the forearm) may help diagnose the condition

Last update : 01/01/1970
 

Causative drugs

1

Mercury (Hg) (fluid, metallic, elemental) i.v., i.m.

I.af I - Interstitial/parenchymal lung disease
I.af - Chemical (toxic) pneumonitis
II.b II - Pulmonary edema - Acute lung injury - ARDS
II.b - ARDS - Acute lung injury
II.u II - Pulmonary edema - Acute lung injury - ARDS
II.u - Acute respiratory failure (e.g. from ARDS, ILD, PIE, OP, pulmonary edema or bronchospasm) requiring ECMO
VI.a VI - Pulmonary vasculopathies
VI.a - Pulmonary embolism - Venous thrombosis/thromboembolism
VI.j VI - Pulmonary vasculopathies
VI.j - Mercury pulmonary embolism
XII.s XII - Cardiovascular involvement / toxicity
XII.s - Heart block (bundle branch- or AV-)
XVI.ax XVI - Imaging
XVI.ax - Imaging: Foreign body pulmonary embolism
XVIII.d XVIII - Distinctive patterns - 'Eye-catchers'
XVIII.d - Eye catcher: Mercury embolism (in lung and/or in other tissues)
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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