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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Bosutinib

2

V.ae Pleural effusion, massive

1
Last update : 25/07/2022
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Dasatinib
4
Imatinib
3
Nilotinib
2

Publications

Bosutinib-induced massive pleural effusion: Cross-intolerance with all tyrosine kinase inhibitors.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 2023 Mar;29;511-516 2023 Mar

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