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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Azacitidine

3

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

1
Last update : 04/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Decitabine
1

Publications

Azacitidine-induced cryptogenic organizing pneumonia: a case report and review of the literature.
Journal of medical case reports 2016 Jan 20;10;15 2016 Jan 20
Pulmonary Complications of Azanucleoside Therapy in Patients with Myelodysplastic Syndrome and Acute Myelogenous Leukemia.
Case reports in hematology 2015;2015;357461 2015
Interstitial lung disease associated with azacitidine use: a case report.
American journal of therapeutics 2012 Mar;19;e98-e100 2012 Mar
Azacitidine-induced interstitial and alveolar fibrosis in a patient with myelodysplastic syndrome.
Pharmacotherapy 2005 May;25;765-8 2005 May

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