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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Fingolimod

1

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 30/05/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Fingolimod-induced asthma deterioration in a patient with relapsing-remitting multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2014 Nov;20;1792-3 2014 Nov
Life-threatening asthma attack during prolonged fingolimod treatment: case report.
Patient preference and adherence 2014;8;987-9 2014

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