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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Carfilzomib

1

XVII.o Nocardia pulmonary/systemic infection

1
Last update : 12/02/2016
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Pulmonary Nocardiosis in a Multiple Myeloma Patient Treated with Proteasome Inhibitors.
The American journal of case reports 2016 Feb 10;17;76-8 2016 Feb 10

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