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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Diclofenac

2

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1
Last update : 08/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Nonsteroidal anti-inflammatory drugs (NSAIDs)
5

Publications

Eosinophilic pneumonia induced by non-steroidal anti-inflammatory drugs: An underestimated risk.
Therapie 2018 Dec;73;473-482 2018 Dec
[Pulmonary infiltrates with blood eosinophilia in a 62-year-old patient].
Der Internist 2003 Aug;44;1037-41 2003 Aug
Diclofenac (Voltaren)-induced eosinophilic pneumonitis. Case report and review of the literature.
Archives of internal medicine 1993 Jul 26;153;1649-52 1993 Jul 26

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