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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Brentuximab vedotin
1
X.g
Hypersensitivity reaction (may manifest with fever and/or skin, throat or airway involvement)
1
Last update :
14/02/2015
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Brentuximab
Publications
Rapid desensitization for brentuximab vedotin (Adceteris) allergy: a case report.
Brentuximab Vedotin Infusion Reaction Management: A Case Study.
Multiple successful desensitizations to brentuximab vedotin: a case report and literature review.