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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Brentuximab vedotin

1

X.g Hypersensitivity reaction (may manifest with fever and/or skin, throat or airway involvement)

1
Last update : 14/02/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
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Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Brentuximab
1

Publications

Rapid desensitization for brentuximab vedotin (Adceteris) allergy: a case report.
Clinical and molecular allergy : CMA 2018;16;22 2018
Brentuximab Vedotin Infusion Reaction Management: A Case Study.
Journal of the advanced practitioner in oncology 2017;8;626-629 2017
Multiple successful desensitizations to brentuximab vedotin: a case report and literature review.
Journal of the National Comprehensive Cancer Network : JNCCN 2014 Apr;12;465-71 2014 Apr

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