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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Status post-lung transplantation

4

XIII.b Lymphoproliferative disease (pulmonary, endobronchial, endothoracic)

4
Last update : 04/05/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
MTOR inhibitors
5

Publications

Posttransplantation lymphoproliferative disorder in lung transplant recipients: a 15-year single institution experience.
Transplantation 2013 Oct 15;96;657-63 2013 Oct 15

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