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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Dexamethasone

2

XII.v Hypertrophic cardiomyopathy

1
Last update : 29/09/2013
 
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Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Corticosteroids, systemic (oral, parenteral)
5

Publications

Hypertrophic Cardiomyopathy After a Single Dose of Dexamethasone in a Preterm Infant.
Pediatrics and neonatology 2015 Aug;56;268-70 2015 Aug
Left ventricular hypertrophy with outflow tract obstruction-a complication of dexamethasone treatment for subglottic stenosis.
International journal of pediatric otorhinolaryngology 2005 Feb;69;271-3 2005 Feb
Hypertrophic cardiomyopathy in preterm infants treated with dexamethasone.
European journal of pediatrics 1997 May;156;394-6 1997 May
[Glucocorticoid-induced hypertrophic cardiomyopathy in premature infants: apropos of 4 cases].
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 1997 Feb;4;152-7 1997 Feb

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