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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Ceritinib

1

XIX.a BAL: An excess proportion of lymphocytes

1
Last update : 26/04/2019
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Ceritinib-related interstitial lung disease improving after treatment cessation without recurrence under either crizotinib or brigatinib: a case report.
Annals of translational medicine 2019 Mar;7;106 2019 Mar

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