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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Deferoxamine

2

XVII.e Pneumocystis jiroveci pneumonia

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Last update : 31/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Pulmonary syndrome in patients with thalassemia major receiving intravenous deferoxamine infusions.
American journal of diseases of children (1960) 1990 May;144;565-9 1990 May
Pneumocystis carinii pneumonia as a complication of desferrioxamine therapy.
British journal of haematology 1988 Nov;70;383-4 1988 Nov

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