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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Deferoxamine

2

II.b ARDS - Acute lung injury

1
Last update : 08/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Pulmonary toxic effects of continuous desferrioxamine administration in acute iron poisoning.
Lancet (London, England) 1992 Mar 21;339;699-701 1992 Mar 21
Pulmonary syndrome in patients with thalassemia major receiving intravenous deferoxamine infusions.
American journal of diseases of children (1960) 1990 May;144;565-9 1990 May

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