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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Dapsone (diaminophenylsulfone)

4

XI.b Chest pain (acute or subacute), lone or prominent

1
Last update : 11/11/2023
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Pyrimethamine-dapsone
1

Publications

A Chest Pain Conundrum: Dapsone-Induced Methemoglobinemia in a Heart Transplant Patient.
Cureus 2023 Oct;15;e46690 2023 Oct

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