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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Dapsone (diaminophenylsulfone)

4

I.b Pneumonitis (ILD)

1
Last update : 28/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Pyrimethamine-dapsone
1

Publications

Severe dapsone hypersensitivity syndrome in a child.
Korean journal of pediatrics 2013 Jun;56;260-4 2013 Jun
Dapsone-induced hypersensitivity pneumonitis mimicking Pneumocystis carinii pneumonia in a patient with AIDS.
The American journal of the medical sciences 2004 Mar;327;163-5 2004 Mar

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