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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Breast implants - Augmentation mammaplasty (w/wo evidence for leakage/rupture)

4

X.s Vasculitis, pulmonary (w/wo AH), extrapulmonary, systemic: ANCA-positive

1
Last update : 13/11/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Silicone, fluid
5

Publications

Microscopic Polyangiitis following Silicone Exposure from Breast Implantation.
Case reports in nephrology 2014;2014;902089 2014
Microscopic polyangiitis after silicone breast implantation.
Clinical and experimental nephrology 2005 Sep;9;252-4 2005 Sep
Vasculitis following implantation of a ventriculoperitoneal shunt tube made of silicone.
Modern rheumatology 2003 Mar;13;73-5 2003 Mar

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