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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Breast implants - Augmentation mammaplasty (w/wo evidence for leakage/rupture)

4

I.b Pneumonitis (ILD)

1
Last update : 13/02/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Silicone, fluid
5

Publications

Chronic Pulmonary Silicone Embolism Related to Saline Breast Implants.
Annals of the American Thoracic Society 2016 Jan;13;139-41 2016 Jan
Chronic silicone embolism syndrome due to PIP breast implant leakage – a new entity?
Histopathology 2015 May;66;904-6 2015 May
Increasing pulmonary infiltrates in a 72-year-old woman with metastatic breast cancer.
Chest 2014 Dec;146;e208-e211 2014 Dec
Autoimmune/inflammatory syndrome induced by adjuvants causing myositis and pulmonary fibrosis.
The Israel Medical Association journal : IMAJ 2013 Nov;15;720-1 2013 Nov
Pneumonitis caused by silicone gel following breast implant rupture.
Irish journal of medical science 2010 Mar;179;141-5 2010 Mar
[Interstitial pneumonia associated with human adjuvant disease which developed 30 years after silicone augmentation mammoplasty].
Nihon Kyobu Shikkan Gakkai zasshi 1997 Oct;35;1093-8 1997 Oct

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