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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Apixaban

2

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

1
Last update : 02/11/2017
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anticoagulants, direct oral (anti-thrombin, -IIa, -Xa) - NOAC
3

Publications

A case of apixaban-associated idiopathic interstitial pneumonia.
Cardiology journal 2022;29;364-365 2022
Development of Interstitial Lung Disease after Initiation of Apixaban Anticoagulation Therapy.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2016 Jul;25;1767-1769 2016 Jul

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