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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Rivaroxaban

2

V.n Hemopericardium - Bloody pericardial effusion

1
Last update : 11/08/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anticoagulants, direct oral (anti-thrombin, -IIa, -Xa) - NOAC
3

Publications

A Complicated Case of Transient Constrictive Pericarditis Secondary to Rivaroxaban-Associated Hemopericardium.
JACC. Case reports 2020 Oct;2;1947-1950 2020 Oct
Spontaneous, Life-Threatening Hemorrhagic Cardiac Tamponade Secondary to Rivaroxaban.
American journal of therapeutics 2016;23;e1128-31 2016
Isolated hemopericardium associated with rivaroxaban: first case report.
Pharmacotherapy 2014 Sep;34;e169-72 2014 Sep
Life-threatening haemorrhagic pericarditis associated with rivaroxaban.
International journal of cardiology 2014 Jun 15;174;e75-6 2014 Jun 15

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