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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Rivaroxaban

2

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

1
Last update : 10/05/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anticoagulants, direct oral (anti-thrombin, -IIa, -Xa) - NOAC
3

Publications

Late Onset of Rivaroxaban-Associated Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis.
Journal of investigative medicine high impact case reports 2023;11;23247096231207689 2023
Fatal pulmonary hemorrhage after taking anticoagulation medication.
Respiratory medicine case reports 2015;15;66-70 2015
Pulmonary haemorrhage from therapeutic rivaroxaban use: chest radiograph consolidation is not always infection!
Emergency medicine Australasia : EMA 2014 Jun;26;318-9 2014 Jun

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