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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Aconite

2

XII.l Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

1
Last update : 07/08/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Herb-induced cardiotoxicity from accidental aconitine overdose.
Singapore medical journal 2015 Jul;56;e116-9 2015 Jul
Various morphologies of bidirectional ventricular tachycardia caused by aconite "Torikabuto" poisoning.
Journal of cardiology cases 2013 Feb;7;e42-e44 2013 Feb

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