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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cyclosporine

2

XVII.e Pneumocystis jiroveci pneumonia

1
Last update : 06/05/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Long-term outcome of treatment with intravenous cyclosporin in patients with severe ulcerative colitis.
Inflammatory bowel diseases 2004 Mar;10;73-8 2004 Mar
Cyclosporin treatment for ulcerative colitis complicated by fatal Pneumocystis carinii pneumonia.
BMJ (Clinical research ed.) 1997 Feb 01;314;363-4 1997 Feb 01
Cyclosporine therapy and refractory Pneumocystis carinii pneumonia. A potential association.
Archives of surgery (Chicago, Ill. : 1960) 1987 Sep;122;1034-5 1987 Sep

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