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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cyclosporine

2

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

1
Last update : 15/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Long-term outcome of treatment with intravenous cyclosporin in patients with severe ulcerative colitis.
Inflammatory bowel diseases 2004 Mar;10;73-8 2004 Mar
IgE-mediated anaphylaxis after first intravenous infusion of cyclosporine.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2001 Sep;87;243-5 2001 Sep
Cyclosporine-induced anaphylaxis.
The Annals of pharmacotherapy 2000;34;858-61 2000

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