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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Phosphate

1

IX.c Chest wall muscle rigidity - Stiff/wooden chest

1
Last update : 05/09/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Severe hypocalcemic tetany and respiratory failure in an infant given oral phosphate soda.
Pediatric emergency care 2006 Feb;22;118-20 2006 Feb

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