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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Fluorescein

1

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

1
Last update : 22/08/2013
 
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Diagnosing DIRD
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Drug and radiation history
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Drug singularity - Correct identification of the drug
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Consistent timing of exposure v. onset of symptoms
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Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Dyes
3

Publications

Anaphylaxis caused by intravenous fluorescein: clinical characteristics and review of literature.
Internal and emergency medicine 2014 Apr;9;325-30 2014 Apr
Anaphylaxis following intravenous fluorescein angiography in a vitreoretinal clinic: report of 4 cases.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 2009 Aug;44;444-5 2009 Aug
An autopsy case of fatal anaphylactic shock following fluorescein angiography: a case report.
Medicine, science, and the law 2004 Jul;44;264-5 2004 Jul
Hazards of intravenous indigo carmine, fluorescein, and methylene blue.
Texas medicine 1980 Oct;76;49-51 1980 Oct

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