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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Contraceptive drugs or pills (oral)

3

VI.c Pulmonary veno-occlusive disease

1
Last update : 14/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Rapidly progressive pulmonary venoocclusive disease in young women taking oral contraceptives.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2012 Sep;31;1031-6 2012 Sep
Fatal pulmonary venoocclusive disease after use of oral contraceptives.
American heart journal 1992 Dec;124;1643-4 1992 Dec

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