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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Anticoagulants, direct oral (anti-thrombin, -IIa, -Xa) - NOAC

3

VIII.b Hematoma of/around central airway wall potentially causing UAO

1
Last update : 17/05/2021
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anticoagulants, oral (vitamin K antagonists-VKA)
5
Apixaban
2
Dabigatran
2
Edoxaban
1
Rivaroxaban
2

Publications

Spontaneous retropharyngeal haematoma with direct oral anticoagulant medication.
BMJ case reports 2021 May 13;14; 2021 May 13
Retropharyngeal Hematoma under Rivaroxaban: A Rare Entity to Know for Its Risk of Airway Obstruction.
Journal of the Belgian Society of Radiology 2021 Mar 16;105;15 2021 Mar 16

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