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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Anticoagulants, direct oral (anti-thrombin, -IIa, -Xa) - NOAC

3

V.n Hemopericardium - Bloody pericardial effusion

1
Last update : 12/08/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anticoagulants, oral (vitamin K antagonists-VKA)
5
Apixaban
2
Dabigatran
2
Edoxaban
1
Rivaroxaban
2

Publications

Hemorrhagic Cardiac Tamponade Associated with Apixaban: A Case Report and Systematic Review of Literature.
Cardiovascular revascularization medicine : including molecular interventions 2019 Nov;20;15-20 2019 Nov
Spontaneous, Life-Threatening Hemorrhagic Cardiac Tamponade Secondary to Rivaroxaban.
American journal of therapeutics 2016;23;e1128-31 2016
Isolated hemopericardium associated with rivaroxaban: first case report.
Pharmacotherapy 2014 Sep;34;e169-72 2014 Sep

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