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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Clopidogrel

2

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Diffuse alveolar hemorrhage: a retrospective study from a tertiary care center.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 2024 Oct 28;; 2024 Oct 28
Pulmonary alveolar hemorrhage mimicking a pneumopathy: a rare complication of dual antiplatelet therapy for ST elevation myocardial infarction.
The Pan African medical journal 2016;24;308 2016
Pulmonary Alveolar Hemorrhage after Clopidogrel Use for ST Elevation Myocardial Infarction.
Korean circulation journal 2013 Jul;43;497-9 2013 Jul
[Pulmonary haemorrhage and haemothorax after massive ingestion of clopidogrel as a suicide attempt].
Archivos de bronconeumologia 2009 Nov;45;570-1 2009 Nov
Massive pulmonary haemorrhage complicating the treatment of acute coronary syndrome.
Heart (British Cardiac Society) 2004 Mar;90;e15 2004 Mar
Diffuse alveolar hemorrhage after clopidogrel use.
The Journal of invasive cardiology 2001 Jul;13;535-7 2001 Jul

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