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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Panitumumab

1

II.b ARDS - Acute lung injury

1
Last update : 29/07/2018
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Panitumumab-induced pulmonary toxicity.
Current oncology (Toronto, Ont.) 2019 Oct;26;e700-e702 2019 Oct
Fatal interstitial lung disease caused by Panitumumab-containing chemotherapy regimen.
Ecancermedicalscience 2018;12;841 2018

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