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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Ethanol (anhydrous)

1

VI.l Acute pulmonary vasoconstriction and PHT

1
Last update : 05/02/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
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Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Pulmonary hypertensive crisis following ethanol sclerotherapy for a complex vascular malformation.
Journal of perinatology : official journal of the California Perinatal Association 2014 Sep;34;713-5 2014 Sep
Acute cor pulmonale and right heat failure complicating ethanol ablative therapy: anesthetic and radiologic considerations and management.
Cardiovascular and interventional radiology 2013 Oct;36;1213-20 2013 Oct
Changes in pulmonary artery pressures during ethanol sclerotherapy for arteriovenous malformations: identifying the most vulnerable period.
Clinical radiology 2011 Jul;66;639-44 2011 Jul
Pulmonary artery pressure changes during ethanol embolization procedures to treat vascular malformations: can cardiovascular collapse be predicted?
Journal of vascular and interventional radiology : JVIR 2006 Feb;17;253-62 2006 Feb

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