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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Gases
5
XII.a
Left or biventricular dysfunction/failure
2
Last update :
22/02/2016
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Amyl-nitrite, butyl-nitrite, isobutyl-nitrite ('Poppers')
Antidotes
Carbon dioxide (CO2)
Carbon monoxide (CO)
Chemicals
Chlorine gas (dichlorine: Cl2)
Inhalants (volatile substances)
Inhaled anesthetic agents
Methyl bromide
Nitric oxide (NO)
Oxygen (dioxygen, O2)
Propane
Riot control agents (RCA)
Sulfur mustard (mustard gas)
Publications
Inhaled matters of the heart.