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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Gases

5

VIII.c Upper airway obstruction other than angioedema or hematoma

1
Last update : 01/11/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Amyl-nitrite, butyl-nitrite, isobutyl-nitrite ('Poppers')
4
Antidotes
1
Carbon dioxide (CO2)
2
Carbon monoxide (CO)
5
Chemicals
5
Chlorine gas (dichlorine: Cl2)
5
Inhalants (volatile substances)
5
Inhaled anesthetic agents
3
Methyl bromide
1
Nitric oxide (NO)
4
Oxygen (dioxygen, O2)
4
Propane
1
Riot control agents (RCA)
5
Sulfur mustard (mustard gas)
3

Publications

Acute laryngeal and bronchial obstruction after CS (o-chlorobenzylidenemalononitrile) gas inhalation.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2009 Feb;266;301-4 2009 Feb

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