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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Hydrocarbons (petrochemicals: petroleum, petrolatum, paraffin, vaseline, naphta, jet fuel (kerosene), Diesel, gasoil), ointments, salad oil, variegated oils, butter). Aspirated

5

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

1
Last update : 05/08/2016
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
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Causality assessment
More detailed checklist
See also under
Kerdane
5
Paraffin-Vaseline-Oil-Lipids (Mineral or other) p.o./inhaled/aspirated
5

Publications

Study of Acute Exogenous Lipoid Pneumonia.
Indian journal of pediatrics 2016 Aug;83;787-91 2016 Aug
Toxicity with intravenous injection of naphtha in man.
Clinical toxicology 1980 May;16;335-43 1980 May

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