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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Hydrocarbons (petrochemicals: petroleum, petrolatum, paraffin, vaseline, naphta, jet fuel (kerosene), Diesel, gasoil), ointments, salad oil, variegated oils, butter). Aspirated

5

I.j Exogenous lipoid pneumonia (subacute, acute)

5
Last update : 20/08/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Kerdane
5
Paraffin-Vaseline-Oil-Lipids (Mineral or other) p.o./inhaled/aspirated
5

Publications

Lipoid pneumonia induced by aspiration of liquid paraffin.
Annals of agricultural and environmental medicine : AAEM 2024 Mar 25;31;144-146 2024 Mar 25
Exogenous lipoid pneumonia due to chronic occult aspiration in a patient with oesophageal colonic interposition.
BMJ case reports 2021 Jun 24;14; 2021 Jun 24
"Diesel siphoner's lung": Exogenous lipoid pneumonia following hydrocarbon aspiration.
Lung India : official organ of Indian Chest Society 2014 Jan;31;63-6 2014 Jan
Lipoid pneumonia in a gas station attendant.
Case reports in pulmonology 2014;2014;358761 2014
Fire-eater's pneumonia after aspiration of liquid paraffin.
The Turkish journal of pediatrics 2006;48;85-8 2006
Exogenous lipoid pneumonia due to nasal application of petroleum jelly.
Chest 1994 Mar;105;968-9 1994 Mar

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