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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cement (bone cement, kyphoplasty, vertebroplasty)

5

XII.bd Perforation of the heart - Cardiac rupture

2
Last update : 24/09/2023
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Vertebroplasty (kyphoplasty)
4

Publications

Case report: Inspiration from a rare fatal heart perforation after percutaneous vertebroplasty.
Frontiers in surgery 2023;10;1227056 2023
Fatal cardiac perforation and pulmonary embolism of leaked cement after percutaneous vertebroplasty.
Journal of forensic and legal medicine 2019 Apr;63;48-51 2019 Apr

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